Microbiology & Immunology Publications

Micronutrient supplemented probiotic yogurt for HIV-infected adults taking HAART in London, Canada

Document Type

Article

Publication Date

9-1-2000

Journal

FEMS Microbiology Letters

Volume

190

Issue

1

First Page

177

Last Page

180

URL with Digital Object Identifier

10.1016/S0378-1097(00)00331-1

Abstract

Lactobacilli have been shown to be important in the maintenance of the healthy urogenital flora. One strain, Lactobacillus fermentum RC-14, releases surface-active components which can inhibit adhesion of uropathogenic bacteria. Using a quantitative method for determining inhibition of adhesion, a protein with high anti-adhesive properties against Enterococcus faecalis 1131 was purified. The N-terminal sequence of the 29-kDa protein was identical to that of a collagen-binding protein from Lactobacillus reuteri NCIB 11951, and exhibited close homology with a basic surface protein from L. fermentum BR11. The results suggest that this anti-adhesive cell surface protein of Lactobacillus could protect against uropathogens by preventing their adhesion. (C) 2000 Published by Elsevier Science B.V.

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