Department of Medicine Publications
As the largest department within the Schulich School of Medicine and Dentistry, the Department of Medicine hosts a vast range of research in its divisions. Research areas include cardiology, clinical immunology and allergy, clinical pharmacology, dermatology, critical care and emergency medicine, endocrinology and metabolism, gastroenterology, hematology, molecular toxicology, nephrology, respirology, and rheumatology.
Visit the Department of medicine website for additional information.
Submissions from 1999
Specific CD3{varepsilon} Epsilon Association of a Phosphodiesterase 4B Isoform Determines Its Selective Tyrosine Phosphorylation after CD3 Ligation, Miren L. Baroja, Lenora B. Cieslinski, Theodore J. Torphy, Ronald L. Wange, and Joaquín Madrenas
Protecting Human Research Subjects: Case-Based Learning for Canadian Research Ethics Boards and Researchers, Françoise Baylis, A. Ireland, David Kaufman, and Charles Weijer
Duty and Healing: Foundations of a Jewish Bioethic, Benjamin Freedman and Charles Weijer
CD40-deficient Dendritic Cells Producing Interleukin-10, but not Interleukin-12, Induce T-cell Hyporesponsiveness In Vitro and Prevent Acute Allograft Rejection, J. X. Gao, J. Madrenas, W. Zeng, M. J. Cameron, Z. Zhang, J. J. Wang, R. Zhong, and D. Grant
Structuring the Review of Human Genetics Protocols Part-III: Gene Therapy Studies, Kathleen C. Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Roberta M. Palmour, Stanley H. Shapiro, and Benjamin Freedman
Variation in Red Cell Transfusion Practice in the Intensive Care Unit: A Multicentre Cohort Study, Paul C. Hébert, George Wells, Claudio Martin, Martin Tweeddale, John Marshall, Morris Blajchman, Giuseppe Pagliarello, Dean Sandham, Irwin Schweitzer, Denis Boisvert, and Lisa Calder
Cytotoxicity of Sulfonamide Reactive Metabolites: Apoptosis and Selective Toxicity of CD8(+) Cells by the Hydroxylamine of Sulfamethoxazole, David A. Hess, Margaret E. Sisson, Hamza Suria, John Wijsman, Ram Puvanesasingham, Joaquín Madrenas, and Michael J. Rieder
Surgical Technique for Vascularized Thymus Transplantation in Mice, Jifu Jiang, Hao Wang, Joaquin Madrenas, and Robert Zhong
Voting Ourselves Rights: A Critique of the Canadian Medical Association Charter for Physicians, Nuala Kenny, Charles Weijer, and Francoise Baylis
Metalloproteinases Are Involved in Lipopolysaccharide- and Tumor Necrosis Factor-alpha-mediated Regulation of CXCR1 and CXCR2 Chemokine Receptor Expression, Masud H. Khandaker, Gordon Mitchell, Luoling Xu, Joseph D. Andrews, Rajkumari Singh, Harry Leung, Joaquín Madrenas, Stephen S. G. Ferguson, Ross D. Feldman, and David J. Kelvin
Placebo-controlled Studies in Schizophrenia: Ethical and Scientific Perspectives. Panel Discussion, T. M. Lemmens, P. S. Appelbaum, W. Carpenter, C. McCarthy, C. Peterson, D. Streiner, and Charles Weijer
What Do We Mean by "Relevance"? A Clinical and Rhetorical Definition with Implications for Teaching and Learning the Case-presentation Format, Lorelei A. Lingard and R. J. Haber
Teaching and Learning Communication in Medicine: A Rhetorical Approach, Lorelei Lingard and R. J. Haber
Lymphocytes: Antigen-induced Gene Activation, Joaquin Madrenas
CD45 Modulation of CXCR1 and CXCR2 in Human Polymorphonuclear Leukocytes, Gordon B. Mitchell, Masud H. Khandaker, Rahbar Rahimpour, Luoling Xu, Andrew I. Lazarovits, J. Geoffrey Pickering, Hamza Suria, Joaquín Madrenas, David K. Pomerantz, Ross D. Feldman, and David J. Kelvin
Integrating Bioethics and Health Law Into the Canadian Institutes of Health Research, Susan Sherwin, Françoise Baylis, Alan Bernstein, Timothy Caulfield, Bernard Dickens, Jocelyn Downie, Bartha Knoppers, Thérèse Leroux, Neil MacDonald, Michael McDonald, Janet Storch, and Charles Weijer
Physiologic tailoring of therapy for resistant hypertension: 20 years' experience with stimulated renin profiling, J. D. Spence
Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area, J. David Spence, M. Rene Malinow, Peter A. Barnett, Ali J. Marian, David Freeman, and Robert A. Hegele
Cytoskeletal Disruption Induces T Cell Apoptosis by a Caspase-3 Mediated Mechanism, Hamza Suria, Luan A. Chau, Ella Negrou, David J. Kelvin, and Joaquín Madrenas
Another Tuskegee?, Charles Weijer
Consensus-seeking Roundtable on Placebos in Clinical Research, Charles Weijer
Getting Doctors to Listen: Ethics and Outcomes Data in Context, Charles Weijer
Medical Futility: Physicians, not Patients, Call the Shots, Charles Weijer
Placebo-controlled Trials in Schizophrenia: Are They Ethical? Are They Necessary?, Charles Weijer
Protecting Communities in Research: Philosophical and Pragmatic Challenges, Charles Weijer