Department of Medicine Publications

 

As the largest department within the Schulich School of Medicine and Dentistry, the Department of Medicine hosts a vast range of research in its divisions. Research areas include cardiology, clinical immunology and allergy, clinical pharmacology, dermatology, critical care and emergency medicine, endocrinology and metabolism, gastroenterology, hematology, molecular toxicology, nephrology, respirology, and rheumatology.

Visit the Department of medicine website for additional information.

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Submissions from 2000

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Identification of a Novel Mechanism for Endotoxin-mediated Down-modulation of CC Chemokine Receptor Expression, Luoling Xu, Masud H. Khandaker, Jana Barlic, Longsi Ran, Miren L. Borja, Joaquín Madrenas, Rahbar Rahimpour, Kong Chen, Gordon Mitchell, Christopher M. Tan, Mark DeVries, Ross D. Feldman, and David J. Kelvin

Submissions from 1999

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Specific CD3{varepsilon} Epsilon Association of a Phosphodiesterase 4B Isoform Determines Its Selective Tyrosine Phosphorylation after CD3 Ligation, Miren L. Baroja, Lenora B. Cieslinski, Theodore J. Torphy, Ronald L. Wange, and Joaquín Madrenas

Protecting Human Research Subjects: Case-Based Learning for Canadian Research Ethics Boards and Researchers, Françoise Baylis, A. Ireland, David Kaufman, and Charles Weijer

Duty and Healing: Foundations of a Jewish Bioethic, Benjamin Freedman and Charles Weijer

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CD40-deficient Dendritic Cells Producing Interleukin-10, but not Interleukin-12, Induce T-cell Hyporesponsiveness In Vitro and Prevent Acute Allograft Rejection, J. X. Gao, J. Madrenas, W. Zeng, M. J. Cameron, Z. Zhang, J. J. Wang, R. Zhong, and D. Grant

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Structuring the Review of Human Genetics Protocols Part-III: Gene Therapy Studies, Kathleen C. Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Roberta M. Palmour, Stanley H. Shapiro, and Benjamin Freedman

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Variation in Red Cell Transfusion Practice in the Intensive Care Unit: A Multicentre Cohort Study, Paul C. Hébert, George Wells, Claudio Martin, Martin Tweeddale, John Marshall, Morris Blajchman, Giuseppe Pagliarello, Dean Sandham, Irwin Schweitzer, Denis Boisvert, and Lisa Calder

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Cytotoxicity of Sulfonamide Reactive Metabolites: Apoptosis and Selective Toxicity of CD8(+) Cells by the Hydroxylamine of Sulfamethoxazole, David A. Hess, Margaret E. Sisson, Hamza Suria, John Wijsman, Ram Puvanesasingham, Joaquín Madrenas, and Michael J. Rieder

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Surgical Technique for Vascularized Thymus Transplantation in Mice, Jifu Jiang, Hao Wang, Joaquin Madrenas, and Robert Zhong

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Voting Ourselves Rights: A Critique of the Canadian Medical Association Charter for Physicians, Nuala Kenny, Charles Weijer, and Francoise Baylis

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Metalloproteinases Are Involved in Lipopolysaccharide- and Tumor Necrosis Factor-alpha-mediated Regulation of CXCR1 and CXCR2 Chemokine Receptor Expression, Masud H. Khandaker, Gordon Mitchell, Luoling Xu, Joseph D. Andrews, Rajkumari Singh, Harry Leung, Joaquín Madrenas, Stephen S. G. Ferguson, Ross D. Feldman, and David J. Kelvin

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Placebo-controlled Studies in Schizophrenia: Ethical and Scientific Perspectives. Panel Discussion, T. M. Lemmens, P. S. Appelbaum, W. Carpenter, C. McCarthy, C. Peterson, D. Streiner, and Charles Weijer

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What Do We Mean by "Relevance"? A Clinical and Rhetorical Definition with Implications for Teaching and Learning the Case-presentation Format, Lorelei A. Lingard and R. J. Haber

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Teaching and Learning Communication in Medicine: A Rhetorical Approach, Lorelei Lingard and R. J. Haber

Lymphocytes: Antigen-induced Gene Activation, Joaquin Madrenas

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CD45 Modulation of CXCR1 and CXCR2 in Human Polymorphonuclear Leukocytes, Gordon B. Mitchell, Masud H. Khandaker, Rahbar Rahimpour, Luoling Xu, Andrew I. Lazarovits, J. Geoffrey Pickering, Hamza Suria, Joaquín Madrenas, David K. Pomerantz, Ross D. Feldman, and David J. Kelvin

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Integrating Bioethics and Health Law Into the Canadian Institutes of Health Research, Susan Sherwin, Françoise Baylis, Alan Bernstein, Timothy Caulfield, Bernard Dickens, Jocelyn Downie, Bartha Knoppers, Thérèse Leroux, Neil MacDonald, Michael McDonald, Janet Storch, and Charles Weijer

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Physiologic tailoring of therapy for resistant hypertension: 20 years' experience with stimulated renin profiling, J. D. Spence

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Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area, J. David Spence, M. Rene Malinow, Peter A. Barnett, Ali J. Marian, David Freeman, and Robert A. Hegele

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Cytoskeletal Disruption Induces T Cell Apoptosis by a Caspase-3 Mediated Mechanism, Hamza Suria, Luan A. Chau, Ella Negrou, David J. Kelvin, and Joaquín Madrenas

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Another Tuskegee?, Charles Weijer

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Consensus-seeking Roundtable on Placebos in Clinical Research, Charles Weijer

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Getting Doctors to Listen: Ethics and Outcomes Data in Context, Charles Weijer

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Medical Futility: Physicians, not Patients, Call the Shots, Charles Weijer

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Placebo-controlled Trials in Schizophrenia: Are They Ethical? Are They Necessary?, Charles Weijer