Folic acid supplementation and chronic kidney disease progression

Authors

Christina M. Wyatt, Icahn School of Medicine at Mount Sinai
J. David Spence, Robarts Research InstituteFollow

Document Type

Article

Publication Date

12-1-2016

Journal

Kidney International

Volume

90

Issue

6

First Page

1144

Last Page

1145

URL with Digital Object Identifier

10.1016/j.kint.2016.09.019

Abstract

In contrast to prior studies demonstrating no benefit or even increased harm from B vitamin supplementation in patients with chronic kidney disease, a large randomized trial from China recently demonstrated small but statistically significant reductions in the risk of first stroke and chronic kidney disease progression with the addition of folic acid to enalapril in adults with hypertension. Differences in the study population and study intervention may explain these discordant results.