Document Type
Article
Publication Date
7-1-2020
Journal
British journal of sports medicine
Volume
54
Issue
13
First Page
771
Last Page
775
URL with Digital Object Identifier
https://doi: 10.1136/bjsports-2018-100231.
Abstract
OBJECTIVES: We systemically reviewed published studies that evaluated aerobic exercise interventions in patients with knee osteoarthritis (OA) to: (1) report the frequency, intensity, type and time (FITT) of exercise prescriptions and (2) quantify the changes in markers of cardiovascular health and systemic inflammation.
DATA SOURCES: PubMed, CINAHL, Scopus; inception to January 2019.
ELIGIBILITY CRITERIA: Randomised clinical trials (RCT), cohort studies, case series.
DESIGN: We summarised exercise prescriptions for all studies and calculated effect sizes with 95% CIs for between-group (RCTs that compared exercise and control groups) and within-group (pre-post exercise) differences in aerobic capacity (VO
RESULTS: Interventions from 49 studies were summarised; 8% (4/49) met all FITT guidelines; 16% (8/49) met all or most FITT guidelines. Fourteen studies (10 RCTs) reported at least one marker of cardiovascular health or systemic inflammation. Mean differences (95% CI) indicated a small to moderate increase in VO
CONCLUSIONS: In studies of aerobic exercise in patients with knee OA, very few interventions met guideline-recommended dose; there were small to moderate changes in markers of cardiovascular health and no decrease in markers of systemic inflammation. These findings question whether aerobic exercise is being used to its full potential in patients with knee OA.
PROSPERO REGISTRATION NUMBER: CRD42018087859.
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