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Submissions from 2010

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Effects of Intensive Medical Therapy on Microemboli and Cardiovascular Risk in Asymptomatic Carotid Stenosis, J. David Spence, Victoria Coates, Hector Li, Arturo Tamayo, Claudio Muñoz, Daniel G. Hackam, Maria DiCicco, Janine DesRoches, Chrysi Bogiatzi, Jonathan Klein, Joaquim Madrenas, and Robert A. Hegele

Submissions from 2009

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Toll-like Receptor 2 Ligands on the Staphylococcal Cell Wall Downregulate Superantigen-induced T Cell Activation and Prevent Toxic Shock Syndrome, Thu A. Chau, Michelle L. McCully, William Brintnell, Gary An, Katherine J. Kasper, Enrique D. Vinés, Paul Kubes, S. M. Mansour Haeryfar, John K. McCormick, Ewa Cairns, David E. Heinrichs, and Joaquín Madrenas

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Attenuation of Massive Cytokine Response to the Staphylococcal Enterotoxin B Superantigen by the Innate Immunomodulatory Protein Lactoferrin, J. L. Hayworth, K. J. Kasper, M. Leon-Ponte, C. A. Herfst, D. Yue, W. C. Brintnell, D. M. Mazzuca, D. E. Heinrichs, E. Cairns, J. Madrenas, D. W. Hoskin, J. K. McCormick, and S. M. M. Haeryfar

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Structure-function Analysis of the CTLA-4 Interaction with PP2A, Wendy A. Teft, Thu A. Chau, and Joaquín Madrenas

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Tumor Suppression by Phospholipase C-beta3 via SHP-1-mediated Dephosphorylation of Stat5, Wenbin Xiao, Hong Hong, Yuko Kawakami, Yuko Kato, Dianqing Wu, Hiroki Yasudo, Akiko Kimura, Hiromi Kubagawa, Luigi F. Bertoli, Randall S. Davis, Luan A. Chau, Joaquin Madrenas, Cyrus C. Hsia, Anargyros Xenocostas, Thomas J. Kipps, Lothar Hennighausen, Atsushi Iwama, Hiromitsu Nakauchi, and Toshiaki Kawakami

Submissions from 2008

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RIP2 Is Required for NOD Signaling But Not for Th1 Cell Differentiation and Cellular Allograft Rejection, T. Fairhead, D. Lian, Michelle L. McCully, B. Garcia, R. Zhong, and J. Madrenas

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Mesenchymal Stem Cells and Their Use as Cell Replacement Therapy and Disease Modelling Tool, J. García-Castro, C. Trigueros, Joaquin Madrenas, J. A. Pérez-Simón, R. Rodriguez, and P. Menendez

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Molecular Requirements for MHC Class II {alpha}-Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C, Katherine J. Kasper, Wang Xi, A. K. M. Nur-Ur Rahman, Mohammed M. Nooh, Malak Kotb, Eric J. Sundberg, Joaquín Madrenas, and John K. McCormick

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Modulation of T Cell Activation by Stomatin-Like Protein 2, Mark G. Kirchhof, Luan A. Chau, Caitlin D. Lemke, Santosh Vardhana, Peter J. Darlington, Maria E. Márquez, Roy Taylor, Kamilia Rizkalla, Isaac Blanca, Michael L. Dustin, and Joaquín Madrenas

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The Future of RIP2/RICK/CARDIAK as a Biomarker of the Inflammatory Response to Infection, Michelle L. McCully, Todd Fairhead, Peter G. Blake, and Joaquin Madrenas

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Receptor-interacting Protein-2 Deficiency Delays Macrophage Migration and Increases Intracellular Infection during Peritoneal Dialysis-associated Peritonitis, Michelle L. McCully, Todd Fairhead, Chantal S. Colmont, Federico C. Beasley, David E. Heinrichs, Peter G. Blake, Nicholas Topley, and Joaquín Madrenas

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Therapeutic Benefits of Regulating Inflammation in Autoimmunity, Enayat Nikoopour, Jordan Ari Schwartz, and Bhagirath Singh

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Dendritic Cell Differentiation Induced by a Self-Peptide Derived from Apolipoprotein E, Tracey A. Stephens, Enayat Nikoopour, Beverly J. Rider, Matilde Leon-Ponte, Thu A. Chau, Sebastian Mikolajczak, Pratibha Chaturvedi, Edwin Lee-Chan, Richard A. Flavell, S M Mansour Haeryfar, Joaquin Madrenas, and Bhagirath Singh

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Characterization of Oligomers Induced by Inverse Agonists of CTLA-4, Wendy A. Teft and Joaquín Madrenas

Submissions from 2007

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Crystal Structure of the Streptococcal Superantigen SpeI and Functional Role of a Novel Loop Domain in T Cell Activation by Group V Superantigens, Jean-Nicholas P. Brouillard, Sebastian Günther, Ashok K. Varma, Irene Gryski, Christine A. Herfst, A. K. M. Nur-ur Rahman, Donald Y. M. Leung, Patrick M. Schlievert, Joaquin Madrenas, Eric J. Sundberg, and John K. McCormick

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T Cell Signalling Induced by Bacterial Superantigens, Clara Bueno, Gabriel Criado, John K. McCormick, and Joaquín Madrenas

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Receptor-interacting Protein 2 Is a Marker for Resolution of Peritoneal Dialysis-associated Peritonitis, Michelle L. McCully, M. L. Baroja, T. A. Chau, A. K. Jain, L. Barra, A. Salgado, P. G. Blake, and Joaquin Madrenas

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Molecular Determinants of Inverse Agonist Activity of Biologicals Targeting CTLA-4, Wendy A. Teft and Joaquín Madrenas

Submissions from 2006

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Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway, Clara Bueno, Caitlin D. Lemke, Gabriel Criado, Miren L. Baroja, Stephen S. G. Ferguson, A. K. M. Nur-Ur Rahman, Constantine D. Tsoukas, John K. McCormick, and Joaquin Madrenas

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A Synergistic Effect Between PG490-88 and Tacrolimus Prolongs Renal Allograft Survival in Monkeys, G. Chen, H. Sun, J. Arp, B. Garcia, X. Wang, Y. Wise, W. Liu, S. Ramcharran, X. Huang, Y. Xiang, H. Yang, Z. Fang, J. Madrenas, Y. Sudo, K. Tamura, and R. Zhong

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Membrane Compartmentalization during T Cell Receptor Signalling and Immunological Synapse Formation, M. G. Kirchhof and J. Madrenas

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Dendritic Cells as Arbiters of Peritoneal Immune Responses, Michelle L. McCully and Joaquín Madrenas

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Molecular Basis of TCR Selectivity, Cross-Reactivity, and Allelic Discrimination by a Bacterial Superantigen: Integrative Functional and Energetic Mapping of the SpeC-Vbeta2.1 Molecular Interface, A. K. M. Nur-ur Rahman, Christine A. Herfst, Beenu Moza, Stephanie R. Shames, Luan A. Chau, Clara Bueno, Joaquín Madrenas, Eric J. Sundberg, and John K. McCormick

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Wilms’ Tumor 1–Associating Protein Regulates the Proliferation of Vascular Smooth Muscle Cells, Theodore W. Small, Zuzana Bolender, Clara Bueno, Caroline O'Neil, Zengxuan Nong, Walter Rushlow, Nagalingham Rajakumar, Christopher Kandel, Jennifer Strong, Joaquin Madrenas, and J. Geoffrey Pickering

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A Molecular Perspective of CTLA-4 Function, Wendy A. Teft, Mark G. Kirchhof, and Joaquín Madrenas