The Modulation of LFP Characteristics In The Freely Moving Common Marmoset
Abstract
The hippocampus is a neural structure critical for navigation. Neurons in this region, along with others, create a functional network which generates large-amplitude modulations known as local field potential (LFP) activity. Prior LFP research has predominantly used rodent animal models, however recent studies have shown that frequencies associated with navigation in other mammals do not correlate to those of the rodent. We hypothesized that LFP characteristics in the common marmoset are modulated by the speed and axis of travel of the animal. Two marmosets were placed in a free moving 3-dimensional environment where movement and neurological activity were recorded. Results showed LFP modulation based on movement, including significant changes in power with movement speed and vertical motion. We provide evidence of theta bout activity and other non-rodent-like characteristics, prompting discussion on the generalization of findings in rodent models such as mice and rats to primate navigation.