“Standing Up” to Type 2 Diabetes
Abstract
Introduction: The overall objectives of this dissertation are to 1) summarize the relationship between sedentary behaviour (SB) and cardiometabolic health and 2) develop an effective, feasible, and acceptable intervention to reduce/ break up SB in adults with T2D.
Methods: Objective 1 was fulfilled by conducting an umbrella review on the relationship between SB and cardiometabolic health. Objective 2 was accomplished by conducting a systematic review on interventions that aim to reduce/ break up SB in adults with T2D, qualitatively exploring the perceptions of adults with T2D, and piloting a 6-week (6-week follow-up) mHealth HAPA-based intervention in adults with T2D.
Results: The umbrella review (N=63) suggest that SB is associated, independent of physical activity (PA), with cardiometabolic diseases and biomarkers. The systematic reviews’ (N=22) meta-analysis of short-term SB interventions found significant improvement in glucose compared to control (SMD -0.819, 95% CI -1.255, -0.383, p
Conclusions: SB is associated, independent of PA, with cardiometabolic diseases and biomarkers. Reducing SB appears to be a feasible/ acceptable/ sustainable behaviour change in adults with T2D that could lead to improvements in their glycemic control and thus, should continue to be investigated.