Understanding the Determinants of the Cost of Coronary Artery Bypass Graft Surgery
Abstract
Introduction: The relationship between patient demographics, clinical factors, and cost of coronary artery bypass graft (CABG) is complex. Investigation of these relationships is important to aid clinical practice and inform reimbursement models. This thesis analyzes multiple different domains in order to understand the significant factors that impact the cost of CABG at the London Health Sciences Centre (LHSC).
Methods: Model selection, construction of nested descriptive models, exploration of mediation analysis of the impact of peri-operative factors and cost through length of stay, and construction of estimative models were performed.
Results: Several baseline characteristics, socio-demographics, peri-operative variables, and post-operative variables were found to be significant drivers of cost. Some of these include having dementia upon admission, experiencing major complications, and having longer length of stay.
Discussion: Through analysis of multiple domains, we begin to develop an understanding of the significant factors that impact the cost of CABG procedures at the LHSC.