Degree
Master of Science
Program
Medical Biophysics
Collaborative Specialization
Musculoskeletal Health Research
Supervisor
Holdsworth, David W.
2nd Supervisor
Teeter, Matthew G.
Co-Supervisor
Abstract
In the clinical setting, weight-bearing static 2D radiographic imaging and supine 3D radiographic imaging modalities are used to evaluate radiographic changes such as, joint space narrowing, subchondral sclerosis, and osteophyte formation. These respective imaging modalities cannot distinguish between tissues with similar densities (2D imaging), and do not accurately represent functional joint loading (supine 3D imaging). Recent advances in cone-beam CT (CBCT) have allowed for scanner designs that can obtain weight-bearing 3D volumetric scans. The purpose of this thesis was to analyze, design, and implement advanced imaging techniques to quantify image quality parameters of reconstructed image volumes generated by a commercially-available CBCT scanner, and a novel ceiling-mounted CBCT scanner. In addition, imperfections during rotation of the novel ceiling-mounted CBCT scanner were characterized using a 3D printed calibration object with a modification to the single marker bead method, and prospective geometric calibration matrices.
Recommended Citation
Baronette, Rudy, "Quantitative Analysis of Three-Dimensional Cone-Beam Computed Tomography Using Image Quality Phantoms" (2018). Electronic Thesis and Dissertation Repository. 5797.
https://ir.lib.uwo.ca/etd/5797