Master of Science
Introduction: The most common method of spinal fusion includes pedicle screws instrumentation, either with or without interbody cage fusion. This thesis aimed to develop and test a novel stand-alone intervertebral device that eliminates the need for pedicle screws and rods.
Method: The stand-alone cage was designed in collaboration with spinal surgeons and engineers using computer assisting drawings, and manufactured in titanium by 3D printing. Biomechanical testing comparing the stand-alone cage with standard posterior lumbar interbody fusion (PLIF) in sawbones (n=6) and cadavers (n=8).
Result: Compared to PLIF, the stand-alone cage demonstrated no significant difference in range of flexion, lateral bend or axial rotation in sawbones; however, significant increase in range of extension was observed. Among cadavers, the stand-alone cage demonstrated a significant increase in range of motion (ROM) for flexion, extension, lateral bending to the right and total lateral bend ROM; but no significant increase to ROM in axial rotation.
Conclusion: Due to the increased ROM associated with the stand-alone cage, this devise is not advisable to use as a fusion implant.
Lumbar spine, anatomy, biomechanics, Posterior lumbar fusion, interbody fusion.
Alhelal, Fahad, "Design, development, manufacturing and biomechanical testing of Stand-alone cage for posterior lumbar interbody fusion" (2018). Electronic Thesis and Dissertation Repository. 5648.