Electronic Thesis and Dissertation Repository

Degree

Master of Science

Program

Surgery

Supervisor

Dr.Parham Rasoulinejad

2nd Supervisor

Dr.Chris Bailey

Co-Supervisor

Abstract

Introduction: The most common method of spinal fusion includes pedicle screws instrumentation, either with or without interbody cage fusion. This thesis aimed to develop and test a novel stand-alone intervertebral device that eliminates the need for pedicle screws and rods.

Method: The stand-alone cage was designed in collaboration with spinal surgeons and engineers using computer assisting drawings, and manufactured in titanium by 3D printing. Biomechanical testing comparing the stand-alone cage with standard posterior lumbar interbody fusion (PLIF) in sawbones (n=6) and cadavers (n=8).

Result: Compared to PLIF, the stand-alone cage demonstrated no significant difference in range of flexion, lateral bend or axial rotation in sawbones; however, significant increase in range of extension was observed. Among cadavers, the stand-alone cage demonstrated a significant increase in range of motion (ROM) for flexion, extension, lateral bending to the right and total lateral bend ROM; but no significant increase to ROM in axial rotation.

Conclusion: Due to the increased ROM associated with the stand-alone cage, this devise is not advisable to use as a fusion implant.

Keywords

Lumbar spine, anatomy, biomechanics, Posterior lumbar fusion, interbody fusion.

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