Electronic Thesis and Dissertation Repository

Self-Reported Sleep Quality and Sleep Disturbances in Patients with Vasculitis

Misa Tanaka, Epidemiology and Biostatistics

Abstract

Vasculitis, characterized by inflammation and blood vessel destruction, is becoming a chronic condition due to improved treatments. Inadequate sleep is associated with the development of chronic outcomes like cardiovascular disease, impacting the health-related quality of life (HRQoL) of vasculitis patients. This study aimed to determine the prevalence of diagnosed sleep disorders and other sleep disturbances using validated sleep questionnaires and explore factors associated with sleep disturbances, stratified by sex, in vasculitis patients. We administered an online survey of patients registered with the Vasculitis Patient-Powered Research Network. The study identified a high prevalence of sleep disorders and disturbances, including excessive daytime sleepiness, affecting daily activities. Pain and body mass index were significantly associated with sleep disturbances in both sexes. This is the largest study to date investigating sleep disturbances and the potential risk factors of sleep disturbances in vasculitis patients. Addressing these factors may improve sleep quality and the HRQoL.