Exploring the Effect of Combining Repetitive Transcranial Magnetic Stimulation with Functional Electrical Stimulation Cycling on Lower Extremity Function Following Incomplete Spinal Cord Injury
Abstract
Spinal cord injury (SCI) is a neurological condition that disrupts lower extremity function, limiting mobility and independence. This dissertation explores the feasibility, acceptability, and safety of combining repetitive transcranial magnetic stimulation (rTMS) with functional electrical stimulation (FES) cycling to improve lower extremity function following motor incomplete SCI (iSCI). This study is a case series pilot study in which participants with iSCI underwent a combined protocol of rTMS and FES cycling for six weeks. The results demonstrate the preliminary feasibility, participant acceptability, and safety of combining rTMS and FES cycling. While results varied between participants, one participant showed improvements in walking speed, muscle strength, and functional tests. These findings suggest the potential of pairing rTMS with FES cycling to improve lower extremity function following iSCI. Further studies with larger sample sizes are warranted to confirm efficacy.