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Psychometric Properties of Patient-Reported Outcome Measures in Chronic Pain Conditions with Central Sensitization:- A Systematic Review

Mst Farjana Akhter, The University of Western Ontario

Abstract

Objective: To identify available patient-reported outcome measures (PROMs) used to evaluate central sensitization (CS) manifestations in chronic pain conditions and evaluate the quality of psychometric properties of those instruments.

Methods: A comprehensive search was conducted across multiple databases. Methodological quality and psychometric properties were assessed and summarized using the COSMIN checklist and scoring manual.

Results: A total of fifty-eight studies addressing eight PROMs were identified. The Central Sensitization Inventory (CSI) received the highest overall ratings for most measurement properties among all the instruments, followed by the Pain Sensitivity Questionnaire and Fibromyalgia Survey Questionnaire. Based on pooled data, the test-retest reliability of the CSI was found to be excellent, with an intra-class correlation coefficient of 0.93 (95% CI: 0.91- 0.95) for overall chronic pain conditions.

Conclusion: CSI could be a reliable PROM for chronic pain with CS. More studies should be performed to comprehensively evaluate all measurement properties of the PROMs.