Date of Award
2006
Degree Type
Thesis
Degree Name
Master of Science
Program
Medical Biophysics
Supervisor
Dr. R. Glenn Wells
Second Advisor
Dr. Ting-Yim Lee
Third Advisor
Dr. Jerry Battista
Abstract
Heart disease is a leading cause of death in Canada, and Positron Emission Tomography (PET) is the gold standard for determining the viability of heart tissue following a heart attack. PET images require correction for attenuation, that is, for signal absorption by patient tissues. Attenuation correction (AC), is done via a transmission scan such as Computed Tomography (CT). However, due to the differences between PET and CT scan durations, respiration-induced motion can cause temporal mismatches leading to errors in the reconstructed PET image. This study compares the magnitude of these errors when single-phase CT, respiratory-averaged CT, and 4D CT are used for AC of cardiac PET in an in vivo canine model. The respiratory-averaged CT correction produced maximum percentage differences that were 7 times less than those produced by the single-phase correction. Using a respiratory-averaged CT may provide an accurate form of AC for cardiac PET imaging.
Recommended Citation
Cook, Russell A.H., "ATTENUATION CORRECTION IN CARDIAC PET/CT USING A TIME- AVERAGED CT" (2006). Digitized Theses. 4712.
https://ir.lib.uwo.ca/digitizedtheses/4712