"CELLULAR LOCALIZATION AND EXPRESSION OF HSP70 AND HSFl IN RAT SKELETAL" by Jason R. Travis

Date of Award

2008

Degree Type

Thesis

Degree Name

Master of Science

Program

Kinesiology

Supervisor

Dr. Earl Noble

Abstract

The objective of the present study was to examine the stress-specific and muscle­ specific differences in the localization of Hsp70 and HSFI following two stressful conditions,exerciseandheatshock. Twofastmuscles,theplantaris(PInt)andthewhite vastus (WV) muscles were harvested from adult male Sprague-Dawley rats either 30 min and 24 hr post-exercise (EX) (1 hour treadmill run, 30m∕min, 2% grade) or post-heat shock (HS) (41.5-42.0 °C for 15 min). Western blots demonstrated an ~2 fold and an ~3.5 fold increase in Hsp70 in the Plnt and an ~5.5 fold and an ~9 fold increase in the WV 24 hr post-EX and 24 hr post-HS, respectively (P

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