Date of Award

2010

Degree Type

Thesis

Degree Name

Master of Science

Program

Neuroscience

Supervisor

Dr. Melvyn Goodale

Second Advisor

Dr. Patrick Brown

Third Advisor

Dr. Stefan Everling

Abstract

Patients with damage to V1 can sometimes direct actions towards ‘unseen’ targets located in areas of the visual field that are deemed ‘blind’ on the basis of static perimetry tests. Here, we show that a patient with a complete right homonymous hemianopia after a V1 lesion remains sensitive to the width of objects presented in her blind field but only when reaching out to grasp them in ‘real-time’. A subsequent fMRI experiment indicated that these preserved abilities are likely mediated by spared extra-geniculostriate pathways, while a small “tag” of occipital cortex located at the occipital pole remained unresponsive. Taken together, the results support the view that visually guided movements can be mediated by pathways that do not support visual consciousness.

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