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Chemistry Publications
Document Type
Article
Publication Date
8-30-2007
Journal
Organic letters
Volume
9
Issue
18
First Page
3703
Last Page
3706
URL with Digital Object Identifier
10.1021/ol701797e
Abstract
The first total synthesis of (-)-aplysiallene has been completed in 16 steps and features a key sequential Mukaiyama aerobic oxidative cyclization to prepare the fused bis-THF core. The original stereochemical assignment has been revised as shown.