Chemistry Publications
Document Type
Article
Publication Date
2-18-2014
Journal
Chemical communications (Cambridge, England)
Volume
50
Issue
14
First Page
1668
Last Page
1670
URL with Digital Object Identifier
10.1039/C3CC47775D
Abstract
The Yb(OTf)3 catalyzed [4+2] cycloaddition between donor-acceptor cyclobutanes and nitrosoarenes is disclosed. This method facilitates the synthesis of tetrahydro-1,2-oxazines in good to excellent yields as single diastereomers. Except for a few electron-deficient nitrosoarenes, excellent regioselectivity was observed throughout these studies.