Chemistry Publications
Document Type
Article
Publication Date
4-25-2021
Journal
Contact Dermatitis
Volume
2021
First Page
1
Last Page
8
URL with Digital Object Identifier
https://doi.org/10.1111/cod.13870
Abstract
Background
Earlier laboratory studies have shown that sodium tetrachloropalladate, Myroxylon pereirae, caine mix II, and palladium chloride trigger the release of aluminium (Al) from Finn Chambers (FC).
Objectives
To investigate whether aluminium realease from FC could influence the diagnostic outcome of patch testing with FC.
Method
A retrospective analysis of patch test results from 2010 to 2019 was performed. A two-sided Fisher's exact test was used to calculate any overrepresentation of contact allergy to Al among patients with positive reactions to sodium tetrachloropalladate, Myroxylon pereirae, caine mix II, and palladium chloride.
Results
A total of 5446 patients had been tested with FC during the study period. There was a significant overrepresentation of contact allergy to Al among patients with positive reactions to sodium tetrachloropalladate, Myroxylon pereirae, caine mix II, and palladium chloride. Patients with a strong Al allergy had significantly higher amounts of concomitant reactions to sodium tetrachloropalladate, Myroxylon pereirae, caine mix II, and palladium chloride compared to patients with weak Al allergy. These results were not seen for patients tested with Finn Chambers AQUA.
Conclusion
In patients with contact allergy to Al, patch testing with Finn chambers could give false-positive reactions to sodium tetrachloropalladate, Myroxylon pereirae, caine mix II, and palladium chloride.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Citation of this paper:
Rosholm Comstedt, L, Dahlin, J, Bruze, M, Hedberg, Y, Matura, M, Svedman, C. Patch testing with aluminium Finn Chambers could give false-positive reactions in patients with contact allergy to aluminium. Contact Dermatitis. 2021; 1– 8. https://doi.org/10.1111/cod.13870
Notes
https://onlinelibrary.wiley.com/doi/10.1111/cod.13870
© 2021 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.