Chemistry Publications
Document Type
Article
Publication Date
10-2-2018
Journal
Chemical communications (Cambridge, England)
Volume
54
Issue
79
First Page
11164
Last Page
11167
Abstract
We describe the synthesis of three different phosphonium salts and their reaction with poly(ethylene glycol) dimethacrylate to create cationic hydrogels. The hydrogels were loaded with an anionic dye and an anionic anti-inflammatory drug through ionic interactions and compared with an analogous ammonium gel. The release rates of these anions depended on their structure and pKa values, as well as the pH and ionic strength of the release medium.