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Description

A targeted catalase, packaged and delivered via exosomes intranasally, provides protection for cochlear cells against oxidative stress, the kind of stress that results from loud noise exposure. It is able to cross the blood-brain barrier and does not result in negative outcomes elsewhere in the body.

Publication Date

2018

Publisher

BrainsCAN

City

London

Keywords

Hearing and auditory perception

Disciplines

Neurosciences

Funding

BrainsCAN Support

BrainsCAN Accelerator Grant: Stimulus

Additional BrainsCAN Support

Rodent Cognition Core

Notes

Western Faculty, Group or Institution

Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry

Associated project summary

Development of a novel pharmaceutical to prevent noise-induced hearing loss

(Available in Scholarship @ Western)

Preventing noise-induced hearing loss with a novel pharmaceutical

Included in

Neurosciences Commons

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