Document Type

Article

Publication Date

1-1-2022

Journal

Neurobiology of Aging

Volume

109

First Page

1

Last Page

10

URL with Digital Object Identifier

10.1016/j.neurobiolaging.2021.09.011

Abstract

Sensitivity to repetitions in sound amplitude and frequency is crucial for sound perception. As with other aspects of sound processing, sensitivity to such patterns may change with age, and may help explain some age-related changes in hearing such as segregating speech from background sound. We recorded magnetoencephalography to characterize differences in the processing of sound patterns between younger and older adults. We presented tone sequences that either contained a pattern (made of a repeated set of tones) or did not contain a pattern. We show that auditory cortex in older, compared to younger, adults is hyperresponsive to sound onsets, but that sustained neural activity in auditory cortex, indexing the processing of a sound pattern, is reduced. Hence, the sensitivity of neural populations in auditory cortex fundamentally differs between younger and older individuals, overresponding to sound onsets, while underresponding to patterns in sounds. This may help to explain some age-related changes in hearing such as increased sensitivity to distracting sounds and difficulties tracking speech in the presence of other sound.

Notes

preprint of

Björn Herrmann, Burkhard Maess, Ingrid S. Johnsrude, A neural signature of regularity in sound is reduced in older adults, Neurobiology of Aging, Volume 109, 2022, Pages 1-10, ISSN 0197-4580, https://doi.org/10.1016/j.neurobiolaging.2021.09.011. (https://www.sciencedirect.com/science/article/pii/S019745802100292X)

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