Title

Hormone effects on fMRI and cognitive measures of encoding: Importance of hormone preparation

Document Type

Article

Publication Date

12-1-2006

Journal

Neurology

Volume

67

Issue

11

First Page

2039

Last Page

2041

URL with Digital Object Identifier

10.1212/01.wnl.0000247277.81400.43

Abstract

We compared fMRI and cognitive data from nine hormone therapy (HT)-naive women with data from women exposed to either opposed conjugated equine estrogens (CEE) (n = 10) or opposed estradiol (n = 4). Exposure to either form of HT was associated with healthier fMRI response; however, CEE-exposed women exhibited poorer memory performance than either HT-naive or estradiol-exposed subjects. These preliminary findings emphasize the need to characterize differential neural effects of various HTs. ©2006AAN Enterprises, Inc.

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