Document Type
Article
Publication Date
4-10-2007
Journal
Neuroscience and Biobehavioral Reviews
Volume
31
Issue
4
First Page
585
Last Page
596
URL with Digital Object Identifier
10.1016/j.neubiorev.2006.12.003
Abstract
We argue that many similar findings observed in cognitive, affective, and social neuroimaging research may compose larger processes central to generating self-relevance. In support of this, recent findings from these research domains were reviewed to identify common systemic activation patterns. Superimposition of these patterns revealed evidence for large-scale supramodal processes, which are argued to mediate appraisal of self-relevant content irrespective of specific stimulus types (e.g. words, pictures) and task domains (e.g. induction of reward, fear, pain, etc.). Furthermore, we distinguish between two top-down sub-systems involved in appraisal of self-relevance, one that orients pre-attentive biasing information (e.g. anticipatory or mnemonic) to salient or explicitly self-relevant phenomena, and another that engages introspective processes (e.g. self-reflection, evaluation, recollection) either in conjunction with or independent of the former system. Based on aggregate patterns of activation derived from the reviewed studies, processes in a ventral medial prefrontal cortex (MPFC)-subcortical network appear to track with the former pathway, and processes in a dorsal MPFC-cortical-subcortical network with the latter. As a whole, the purpose of this framework is to re-conceive the functionality of these systems in terms of supramodal processes that more directly reflect the influences of relevance to the self. © 2007 Elsevier Ltd. All rights reserved.
Notes
This is an author-accepted manuscript
The publisher's version is available at:
Schmitz, T. W., & Johnson, S. C. (2007). Relevance to self: A brief review and framework of neural systems underlying appraisal. Neuroscience and biobehavioral reviews, 31(4), 585–596. https://doi.org/10.1016/j.neubiorev.2006.12.003