Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness.
Document Type
Article
Publication Date
1-1-2014
Journal
Front Hum Neurosci
Volume
8
First Page
1028
Last Page
1028
URL with Digital Object Identifier
10.3389/fnhum.2014.01028
Abstract
Progress in neuroimaging has yielded new powerful tools which, potentially, can be applied to clinical populations, improve the diagnosis of neurological disorders and predict outcome. At present, the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements of behavior, with an emerging role for neuroimaging techniques. In this review we focus on white matter alterations measured using Diffusion Tensor Imaging on patients with consciousness disorders, examining the most common diffusion imaging acquisition protocols and considering the main issues related to diffusion imaging analyses. We conclude by considering some of the remaining challenges to overcome, the existing knowledge gaps and the potential role of neuroimaging in understanding the pathogenesis and clinical features of disorders of consciousness.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Notes
© 2015 Cavaliere, Aiello, Di Perri, Fernandez-Espejo, Owen and Soddu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Publisher's version originally as:
Cavaliere C, Aiello M, Di Perri C, Fernandez-Espejo D, Owen AM, Soddu A. Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness. Frontiers in Human Neuroscience 2015; 8, 1028. DOI: 10.3389/fnhum.2014.01028