Document Type
Article
Publication Date
1-1-1998
Journal
Human Brain Mapping
Volume
6
Issue
5-6
First Page
348
Last Page
357
URL with Digital Object Identifier
https://doi.org/10.1002/(SICI)1097-0193(1998)6:5/6<348::AID-HBM4>3.0.CO;2-P
Abstract
The aim of this paper is to illustrate a method for identifying macroscopic anatomical differences among the brains of different populations of subjects. The method involves spatially normalizing the structural MR images of a number of subjects so that they all conform to the same stereotactic space. Multivariate statistics are then applied to the parameters describing the estimated nonlinear deformations that ensue. To illustrate the method, we compared the gross morphometry of male and female subjects. We also assessed brain asymmetry, the effect of handedness, and interactions among these effects.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.