Bone and Joint Institute
Recommendations for Core Outcome Domain Set for Whiplash-Associated Disorders (CATWAD)
Document Type
Article
Publication Date
9-1-2019
Journal
Clinical Journal of Pain
Volume
35
Issue
9
First Page
727
Last Page
736
URL with Digital Object Identifier
10.1097/AJP.0000000000000735
Abstract
© 2019 Wolters Kluwer Health, Inc. All rights reserved. Objective:Inconsistent reporting of outcomes in clinical trials of treatments for Whiplash-associated Disorders (WAD) hinders effective data pooling and conclusions that can be drawn about the effectiveness of tested treatments. The aim of this study was to provide recommendations for core outcome domains that should be included in clinical trials of WAD.Materials and Methods:A 3-step process was used: (1) A list of potential core outcome domains were identified from the published literature. (2) Researchers, health care providers, patients, and insurance personnel participated and rated the importance of each domain via a 3-round Delphi survey. A priori criteria for consensus were established. (3) Experts comprising researchers, health care providers, and a consumer representative participated in a multidisciplinary consensus meeting that made final decisions on the recommended core outcome domains.Results:The literature search identified 63 potential core domains. A total of 223 participants were invited to partake in the Delphi surveys, with 41.7% completing round 1, 45.3% round 2, and 51.4% round 3. Eleven core domains met the criteria for inclusion across the entire sample. After the expert consensus meeting, 6 core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life, and Pain.Discussion:A 3-step process was used to recommend core outcome domains for clinical trials in WAD. Six core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life, and Pain. The next step is to determine the outcome measurement instruments for each of these domains.
Notes
Author-accepted manuscript is openly available from another repository with the University of Southern Denmark through the SDU Research Portal.