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Theses/Dissertations from 2017

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Regulation of Smad anchor necessary for receptor activation (SARA) protein levels by the E3 ubiquitin-protein ligase Smurf2 and Smad7, Sanghyun Lee

Theses/Dissertations from 2016

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Peroxisome Proliferator Activated Receptor Delta in Osteoarthritis, Anusha Ratneswaran

Theses/Dissertations from 2015

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Prenatal Exposure to Bisphenol A Disrupts Fetal Liver Maturation in a Sex-Specific Manner, Bianca DeBenedictis

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Mechanisms of neural precursor cell apoptosis by microglia-derived cytokines, Jennifer Guadagno

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Surfactant and Matrix Metalloproteinase 3 in the Pathogenesis of Acute Lung Injury, Valeria Puntorieri

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Brain Injury and Inflammation and Placental Inflammation in Response to Repetitive Umbilical Cord Occlusions in the Near Term Ovine Fetus, Alex Xu

Theses/Dissertations from 2014

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Pathway-Specific Signaling and its Impact on Fertility: A Focus on the Kisspeptin Receptor, Kiss1r, Maryse R. Ahow

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Roles of P2X7 Receptors in Adipose and Skeletal Tissues of Mice, Kim L. Beaucage

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Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95, Henry A. Dunn

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KISS1R Signaling Promotes Breast Cancer Metastasis, Cameron G-F Goertzen

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Functional role of the striatum in stimulus-response learning: Evidence from functional MRI and patients with Parkinson's disease, Nole M. Hiebert

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ILK modulates stress-induced apoptosis in epidermal keratinocytes, Michelle Im

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A RHOG/ILK/ELMO2/RAC1 Pathways Modulates Microtubule Stability, Bradley C. Jackson

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TAK1 Mediates TGF beta-1 Responses in Gingival Fibroblasts, Hanna Kuk

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Mouse Models of Intervertebral Disc Development, Degeneration and Mechanical Loading, Matthew R. McCann

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Pregestational Diabetes and Congenital Heart Defects: Role of Reactive Oxygen Species, Hoda Moazzen

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Niacin and microvascular endothelial cell response to fatty acid excess and hypoxia, Dominic Pang

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Role of C-Kit Receptor Tyrosine Kinase on INS-1 Cell VEGF-A Expression in Vitro, Alexei Popell

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Characterization of Blood-Derived Human Progenitor Cells for Vascular Regeneration, David Putman

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Regulation of Metabotropic Glutamate Receptor 5 activity by Ca2+/Calmodulin-dependent Protein Kinase IIα, Fitore Raka

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The Implications of Altered Cholinergic Signaling in Cardiac Health and Disease, Ashbeel Roy

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Islet Regenerative Properties of Ex Vivo Expanded Hematopoietic Progenitor Cells, Ayesh K. Seneviratne

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NGN3 Expression in Definitive Endoderm Progenitors Specifies Pancreatic Endocrine Precursors, Ahmed Shah

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Mutations at the 46th residue change properties of Cx50 gap junction channels, Xiaoling Tong

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Characterization of Human 82-kDa Choline Acetyltransferase expression in a newly developed Transgenic Mouse Model, Silke M. Vanvaerenbergh

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Amyloid β Peptides, Signalling and Trafficking of the α7 Nicotine Receptor, Kirk Young

Theses/Dissertations from 2013

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The role of choline acetyltransferase variants in Alzheimer's disease models, Shawn Albers

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Traumatic Injury in vitro Elicits JNK-mediated Human Astrocyte Retraction, but Spares Cerebrovascular Endothelial Cells, Claudia Augustine

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Skin Diseases and Non-Syndromic Hearing Loss Linked to Cx30 Mutations Arise Through Several Distinct Mechanisms, Amy C. Berger

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Transforming growth factor-beta receptor signalling is modulated by integrin-linked kinase, Stellar H. Boo

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Contribution of TRPM2 to Memory Loss in an Alzheimer's Mouse Model, Megan M. Chen

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Characterizing Stomatin-like Protein 2 and its Role in Neuron Survival, Lisa A. Foris

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Atrial Fibrillation-Linked Germline GJA5/Connexin40 Mutants Showed an Increased Hemichannel Function, Matthew D. Hills

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Effects of niacin in human vascular endothelial cells during lipotoxicity, Jennifer M. Hughes-Large

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Prenatal Programming of Hepatic Glucose and Cholesterol Regulation in Male Rat Offspring by Chronic Intermittent Hypoxia, Waseem Iqbal

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Regulation of TRPM2 channels by Fyn kinase, Matthew L. Johnston

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The effect of low and high carbohydrate diets on pulmonary oxygen uptake and muscle deoxygenation kinetics during exercise transitions into the heavy-intensity domain, John Leckie

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A C-terminus Mitochondrial-localization Region and BH3 Domain of Puma are Required for Apoptotic Function, Liz A. Merwin

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Intermittent Hypoxia Affects Leptin and Leptin Receptor Signaling in the Rat Carotid Body, Scott A. Messenger

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Intermittent Hypoxia Alters Metabolic and Cardiovascular Neural Pathways, Jason Michael Moreau

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Aging and Obesity Models in Osteoarthritis, Sara Ohora

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Cholesterol-Mediated Dysfunction of Surfactant Effects of Surfactant Protein-A and Diet-Induced Hypercholesterolemia, Joshua Qua Hiansen

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Molecular Mechanisms Underlying the Early Life Programming of the Liver, Gurjeev Sohi

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Elongation factor 1A-1 and hepatocyte response to fatty acid excess, Alexandra M. Stoianov

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The Role of the Liver X Receptor (LXR) in the Fetal Programming of Hepatic Gluconeogenesis, (Peter) Thin X. Vo

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Ectopic Mineralization of Spinal Tissues in Mice Lacking Equilibrative Nucleoside Transporter 1, Sumeeta Warraich

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The Role of α5GABA(A) Receptors in Brain Inflammation, Jason K. Wong

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Improving Cardiac Repair by Stem Cell Factor Post-Myocardial Infarction, Fuli Xiang

Theses/Dissertations from 2012

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Ginseng Extract Treatment Influences on Preimplantation Development in Vitro, and Pregnancy and Post-Partum Development in the Mouse, Danyka D. Belanger

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The Developmental and Adaptive role of Mitogen Activated Protein Kinase Pathways During Preimplantation Development, Christine E. Bell

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Human Cerebrovascular Endothelial Cell Responses in Severe Sepsis, Christopher J. Blom

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Involvement of Interleukin-33/ST2 in Myocardial Dysfunction in Murine Model of Sepsis, Yoonmi Choe

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KISS1R Induces Human Mammary Epithelial Cell Invasiveness and Promotes Breast Cancer Cell Migration and Invasion via IQGAP1, Donna Cvetkovic

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Modulation of G Protein-Coupled Receptor Intracellular Trafficking and Signal Transduction, Jessica L. Esseltine

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Uncovering Dual Roles for PERK Signaling During Experimentally Induced Pancreatitis, Elena Fazio

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The Role of Glycogen Synthase Kinase 3 Beta in Skeletal Development, J. Ryan Gillespie

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The Effects of Telomerase Inhibition on Cellular Senescence in Fetal Guinea Pig Muscle Cells, Stephanie E. Hallows

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Functional Significance of ILK-ELMO2 Interactions in Epidermal Keratinocytes, Ernest Ho

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DNA Damage and Oxidative Stress Induced-p53 Activity In Astrocytes causes Growth Arrest, Sarah A. Humphrey

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The Distribution and Functional Properties of PMLD-Linked CX47 Mutations on CX47/CX47 Homotypic and CX47/CX43 Heterotypic Gap Junctions, Mi Seong Kim

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The Role of Ca2+/Calmodulin Dependent Protein Kinase II Alpha in Group 1 Metabotropic Glutamate Receptor Endocytosis and Signalling, Stephanie C. Kulhawy

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Transforming Growth Factor Beta Receptor Partitioning: Molecular Mechanisms and Functional Consequences, Sarah E.A. McLean

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Chronic North American Ginseng Administration Alters Metabolic and Cardiovascular Variables in the Rat, Megan J. Migchels

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Gender Does Not Influence the Relationship Between Posterior Cruciate Ligament Design and Patient-Reported Outcomes in Patients Receiving Primary Unilateral Total Knee Arthroplasty, Ryan Milan

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Placental insufficiency resulting in fetal growth restriction alters synaptic development and neuronal myelination in guinea pigs at term, Karolina Piorkowska

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Post-transcriptional regulation of telomerase reverse transcriptase (TERT) in human embryonic stem cells cultured under varying oxygen microenvironments, Lida Radan

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The Role of Transforming Growth Factor Alpha in Osteoarthritis and Skeletal Development, Shirine E. Usmani

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Roles of PGC-1α/PPARs pathway in regulating insulin sensitivity in mouse skeletal muscle cells under prolonged hypoxia, Yunyan Zhang

Theses/Dissertations from 2011

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The Effects of Low Protein during Gestation on Mouse Pancreas Development and Beta Cell Regeneration, Aaron R. Cox

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Morpho-physiological analysis of interneuronal populations in the rat piriform cortex before and after kindling induced epilepsy, Cezar Gavrilovici

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The Vascular Link Between Intrauterine Hypoxia and Postnatal Cardiovascular Pathology, Jennifer A. Thompson

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Mechanisms of Atrial Arrhythmia: Investigations of the Neuro-Myogenic Interface in the Mouse, Jari Michael Tuomi

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Role of Rac1 in myocardial TNF-alpha expression in sepsis, Ting Zhang

Theses/Dissertations from 2010

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The roles of nitric oxide synthases (NOS) in endochondral bone formation, Qian Yan

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Cardiac Adaptation To Chronic Blockade Of Voltage-Gated, L-Type Calcium Channels In The Sarcolemma, Ji Zhou