Faculty
Schulich School of Medicine & Dentistry
Supervisor Name
Eva Turley
Keywords
Triple negative breast cancer, RHAMM, IF, MDA-MB-231, CD44, Has2, p-ERK, Cleaved Caspase 3
Description
1.Compare the levels of proliferation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids as determined by ki67 and Caspase 3 signaling 2.Compare levels of RHAMM, CD44, Has2, and p-ERK activation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids
Acknowledgements
All this work would not be possible without:
Dr. Eva Turley
Cancer Research Society
Breast Cancer Society of Canada
Western University
Lawson Health Research Institute
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Document Type
Poster
Included in
Biological Factors Commons, Body Regions Commons, Cells Commons, Molecular Biology Commons, Oncology Commons
Understanding the role of RHAMM in tumor load– mediated tumor invasiveness of Triple Negative Breast Cancer
1.Compare the levels of proliferation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids as determined by ki67 and Caspase 3 signaling 2.Compare levels of RHAMM, CD44, Has2, and p-ERK activation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids