Master of Arts
Dr. Harry Prapavessis
Background: In a non-smoking population exercise and nicotine have been shown to increase cognition (Guirguis, 2016). In non-deprived smoking model it is unknown if the exercise will provide the same benefit seen in non-smokers.
Methods: A randomized counterbalanced crossover study design was utilized. The primary outcome was working memory accuracy and reaction time measured by n-back assessments (i.e., 3-back).
Results: A repeated measure ANOVA revealed a significant treatment effect for accuracy on the 3-back [F (24) = 8.118, p=.002, n2=.404]. Post-hoc paired sample t-tests uncovered a significant improvement in accuracy from baseline and the exercise condition [t (25) = 2.605, p=.015, d = .511], improvement in accuracy from baseline and the nicotine inhalation condition [t (25) = 3.447, p = .002, d= .676]. Non-significant differences were observed between the two treatments groups [t (25) = .892, p=.381, d=.175]. A repeated measures ANOVA revealed a non-significant treatment effect for RT on the 3-back [F (24) = .428, p=.772, n2=0.021].
Conclusion: Exercise is pragmatically as effective as nicotine in improving acute working memory accuracy without a compromise in reaction time.
Fagan, Matthew, "The Acute Effects of Nicotine and Exercise on Working Memory in Smokers" (2018). Electronic Thesis and Dissertation Repository. 5380.
Available for download on Saturday, May 02, 2020