Electronic Thesis and Dissertation Repository


Master of Science


Medical Biophysics


Dr. Jeffrey Carson


Photoacoustic imaging (PAI) is a hybrid imaging modality that takes advantage of both optical and acoustic techniques for biomedical imaging. It is believed that PAI can successfully assess the margins of lumpectomy specimens in the operating room, decreasing the number of surgeries and wait time for patients. However, current PAI systems do not have sufficient field of view (FOV) to accommodate the size of lumpectomy specimens. In this work, transducer directionality and the use of a shaped matching layer were explored as means to increase the FOV of a staring photoacoustic transducer array. The results indicated that applying a convex matching layer to the face of transducers and directing them toward the centre of the array provides optimal sensitivity throughout the imaging volume. By employing these techniques, any PAI system’s effective FOV can be increased without replacing existing transducers. The optimized system can now be investigated for lumpectomy margin assessment.