Master of Science
Dr. Manuel Montero-Odasso
The study aim was to identify associations between deficits in specific cognitive domains and gait performance in Mild Cognitive Impairment (MCI). Sixty-eight participants with MCI underwent cognitive function testing in executive function (EF), attention, working memory, episodic memory and language domains. Gait was assessed using an electronic walkway (GaitRite®). The means and co-efficient of variation of five gait parameters were evaluated: velocity, stride time, stride length, step width and double support time during single (SG) and dual-task (DT) test conditions Multivariable linear regression analysis demonstrated deficits in EF, working memory and episodic memory were significantly associated with increased gait variability (GV) under both walking test conditions. DT gait revealed additional significant associations between deficits in attention and language domains and increased GV. Deficits in multiple cognitive domains such a language, working and episodic memory are associated with increases in GV. The associations also suggest gait control shares similar neural networks as memory and language.
Gordon, Elyse M., "Specific Cognitive Domains Associated with Gait Performance in Mild Cognitive Impairment" (2014). Electronic Thesis and Dissertation Repository. 2406.