Master of Science
Dr. J. Kevin Shoemaker
Baseline muscle sympathetic nerve activity (MSNA) comparisons of age (young & old, n=40) and cardiovascular disease (CVD) state (young: Y, old: O, metabolic syndrome: MET, coronary artery disease: CAD, chronic heart failure: CHF, n= 36) groups were made to assess which MSNA variable(s) best describe group differences using a MANOVA-based approach across 10 variables. The hypothesis that action potential (AP) variables would better discriminate between groups than integrated variables was not supported. Burst frequency and incidence together significantly differentiated between groups with variability attributed to spikes/min and spikes/100hb removed. Significant group differences were noted for these variables such that Y
Brewer, Danielle N., "Assessing Multi-Unit Muscle Sympathetic Nerve Activity Across Groups: A Multivariate Approach to a Multivariate Concept" (2013). Electronic Thesis and Dissertation Repository. 1338.