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Description

The causes for ASD and DLD are many, complex and largely unknown. One specific cause already identified is mutation of a single gene essential for neuronal development. A useful transgenic rat model has been developed with this mutation that exhibits disabilities very reminiscient of children with ASD or DLD. We will use it to demonstrate that the same tests can show the same disruptions to the auditory system between children with ASD/DLD and this rat model. This model can then be used to undertake further exploration of the impact of ASD/DLD on the auditory system and evaluation of possible behavioural and pharmacological interventions.

Publication Date

2018

Publisher

BrainsCAN

City

London

Keywords

Hearing and auditory perception, Language and speech, Mental health, Neurodevelopment

Disciplines

Neurosciences

Funding

Funding Program

BrainsCAN Accelerator Grant: Stimulus

Additional BrainsCAN Support

Rodent Cognition Core
Imaging Core

Notes

Western Faculty, Group or Institution

Schulich School of Medicine & Dentistry, Department of Anatomy & Cell Biology

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Establishing a translational platform for studying sensory processing in neurodevelopmental disorders

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Neurosciences Commons

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