Title

Role of hybrid brain imaging in neuropsychiatric disorders

Document Type

Article

Publication Date

1-1-2015

Journal

Diagnostics

Volume

5

Issue

4

First Page

577

Last Page

614

URL with Digital Object Identifier

10.3390/diagnostics5040577

Abstract

This is a focused review of imaging literature to scope the utility of hybrid brain imaging in neuropsychiatric disorders. The review focuses on brain imaging modalities that utilize hybrid (fusion) techniques to characterize abnormal brain molecular signals in combination with structural and functional changes that have been observed in neuropsychiatric disorders. An overview of clinical hybrid brain imaging technologies for human use is followed by a selective review of the literature that conceptualizes the use of these technologies in understanding basic mechanisms of major neuropsychiatric disorders and their therapeutics. Neuronal network abnormalities are highlighted throughout this review to scope the utility of hybrid imaging as a potential biomarker for each disorder.

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