Bone and Joint Institute
Document Type
Article
Publication Date
12-1-2017
Journal
Journal of Experimental Orthopaedics
Volume
4
Issue
1
URL with Digital Object Identifier
10.1186/s40634-017-0109-1
Abstract
© 2017, The Author(s). Background: The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images. Methods: Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area. Results: Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm3; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm2. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight. Conclusions: The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Notes
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Originally published as:
Dhollander, A., Malone, A., Price, J. et al. Determination of knee cartilage volume and surface area in beagle dogs: a pilot study. J EXP ORTOP 4, 35 (2017). https://doi.org/10.1186/s40634-017-0109-1