Bone and Joint Institute

Document Type

Article

Publication Date

12-1-2017

Journal

Journal of Experimental Orthopaedics

Volume

4

Issue

1

URL with Digital Object Identifier

10.1186/s40634-017-0109-1

Abstract

© 2017, The Author(s). Background: The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images. Methods: Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area. Results: Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm3; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm2. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight. Conclusions: The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.

Notes

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Originally published as:

Dhollander, A., Malone, A., Price, J. et al. Determination of knee cartilage volume and surface area in beagle dogs: a pilot study. J EXP ORTOP 4, 35 (2017). https://doi.org/10.1186/s40634-017-0109-1

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.