Methods and considerations for the analysis and standardization of assessing muscle sympathetic nerve activity in humans

Authors

Daniel W. White, University of Illinois at Chicago
J. Kevin Shoemaker, Western University
Peter B. Raven, University of North Texas Health Science Center

Document Type

Article

Publication Date

12-1-2015

Journal

Autonomic Neuroscience: Basic and Clinical

Volume

193

First Page

12

Last Page

21

URL with Digital Object Identifier

10.1016/j.autneu.2015.08.004

Abstract

© 2015 Elsevier B.V.. The technique of microneurography and the assessment of muscle sympathetic nerve activity (MSNA) are used in laboratories throughout the world. The variables used to describe MSNA, and the criteria by which these variables are quantified from the integrated neurogram, vary among studies and laboratories and, therefore, can become confusing to those starting to learn the technique. Therefore, the purpose of this educational review is to discuss guidelines and standards for the assessment of sympathetic nervous activity through the collection and analysis of MSNA. This review will reiterate common practices in the collection of MSNA, but will also introduce considerations for the evaluation and physiological inference using MSNA.

Notes

Author-Accepted Manuscript is archived here. Published in final edited form as: Auton Neurosci. 2015 December; 193: 12–21. doi:10.1016/j.autneu.2015.08.004

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