Bone and Joint Institute

Title

Autonomic responses to exercise: Deconditioning/inactivity

Document Type

Article

Publication Date

1-1-2015

Journal

Autonomic Neuroscience: Basic and Clinical

Volume

188

First Page

32

Last Page

35

URL with Digital Object Identifier

10.1016/j.autneu.2014.10.012

Abstract

© 2014 Elsevier B.V. Experimental models of physical inactivity associated with a sedentary lifestyle or extreme forms of inactivity with bed rest or spaceflight affect the balance between parasympathetic and sympathetic nervous system regulation of the cardiovascular system. Deconditioning effects are rapidly seen in the regulation of heart rate to compensate for physical modifications in blood volume and cardiac function. Reflex regulation of cardiovascular control during exercise by metaboreflex and baroreflex is altered by bed rest and spaceflight. These models of extreme inactivity provide a reference to guide physical activity requirements for optimal cardiovascular health.

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