Critical-Size Bone Defects: Is There a Consensus for Diagnosis and Treatment?
Journal of Orthopaedic Trauma
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Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved. There is a significant burden of disease associated with bone defects, and their management is challenging. These injuries have a profound clinical and economic impact, and outcomes are limited by high rates of complication and reoperation, as well as poor functional outcomes. There remains a lack of consensus around definitions, reliable models, and best practices for the surgical management of bone defects. The current state of the literature on bone defects is reviewed here, with a focus on defining critical-size bone defect, the use of the induced membrane technique, the role of biologics, and the management of infected bone defects.