Degree
Master of Engineering Science
Program
Biomedical Engineering
Supervisor
Dr. Amin Rizkalla
Abstract
Surface modification is a well-known approach to enhance the osseointegration of titanium dental implants. In this study, a novel hydrothermal method for coating titanium surfaces with bioactive glass was developed. Our method included sol-gel synthesis of bioactive glass, followed by hydrothermal coating of titanium under different NaOH concentrations. The surface properties of coated substrates were evaluated by scanning electron microscopy, X-ray diffraction, energy dispersive X-ray spectroscopy, and surface profilometry. By varying the alkalinity of the hydrothermal process, different surface topographies, crystalline phases and chemistries could be obtained. Soaking the hydrothermally coated titanium substrates in simulated body fluid resulted in hydroxyapatite deposition, demonstrating bioactivity. All titanium surfaces were biocompatible and the topography of the coated titanium surfaces played a major role in determining the attachment of MC3T3-E1 osteoblastic cells. Our studies suggest that this novel coating method has the potential to improve the osseointegration of dental implants.
Recommended Citation
Gebril, Mohamed, "Bioactive Glass-Ceramic Coating of Titanium Substrates by Alkaline Hydrothermal Process" (2015). Electronic Thesis and Dissertation Repository. 2965.
https://ir.lib.uwo.ca/etd/2965