Electronic Thesis and Dissertation Repository

Degree

Master of Science

Program

Physiology

Supervisor

Femida Gwadry-Sridhar

Abstract

The effect of the interaction between gender and posterior cruciate ligament (PCL) prosthesis design on patient-reported outcomes is an understudied area of research. We evaluated 1613 patients, from the Ontario Joint Replacement Registry (2001-2006), who underwent primary total knee replacement. This study investigated the impact of the gender-PCL design interaction on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) change scores and patient satisfaction, by performing linear regression analysis, using full-adjusted models that also included the gender-PCL prosthesis design interaction variable. PCL prosthesis design did not affect WOMAC change scores or satisfaction (p>0.05). Moreover, Gender did not influence either of the patient-reported outcomes (p>0.05). In addition, the interaction between gender and PCL design did not impact patient-reported outcomes (p>0.05). In conclusion, the surgical preference to retain or sacrifice the PCL should not be influenced by the gender of the patient.