Article Title
Nucleotide Excision Repair in the Three Domains of Life
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Abstract
Nucleotide excision repair (NER) is a vital DNA repair pathway which acts on a wide range of helix-distorting lesions. The importance of this pathway is highlighted by its functional conservation throughout evolution and by several human diseases, such as xeroderma pigmentosum, which are caused by a defective NER pathway. This review summarizes the NER mechanisms present in all three domains of life: eukaryotes, bacteria, and archaea.
Digital Object Identifier
http://dx.doi.org/10.5206/wurjhns.2010-11.1
Recommended Citation
Farnell, David A.
(2011)
"Nucleotide Excision Repair in the Three Domains of Life,"
WURJ: Health and Natural Sciences: Vol. 2:
Iss.
1, Article 1.
DOI: http://dx.doi.org/10.5206/wurjhns.2010-11.1
Available at:
https://ir.lib.uwo.ca/wurjhns/vol2/iss1/1