Paediatrics Publications

Title

High-Risk, High-Reward Genetics in ASD

Document Type

Article

Publication Date

2-5-2020

Journal

Neuron

Volume

105

Issue

3

First Page

407

Last Page

410

URL with Digital Object Identifier

10.1016/j.neuron.2020.01.007

Abstract

In a recent issue of Cell, Satterstrom et al. leverage de novo high-impact variants to identify 102 genes associated with autism spectrum disorder (ASD). Most of these genes have roles in regulation of gene expression or neuronal communication, implicating both developmental and functional changes in ASD.

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