Paediatrics Publications

Title

Intra-abdominal mass and iron deficiency anemia in a 15-year-old boy: Case report and literature review

Document Type

Article

Publication Date

1-1-2014

Journal

Journal of Pediatric Surgery Case Reports

Volume

2

Issue

3

First Page

123

Last Page

125

URL with Digital Object Identifier

10.1016/j.epsc.2014.02.010

Abstract

Castleman's disease is rare lymphoproliferative disorder that typically presents as a mediastinal mass, although 10% of cases may be intra-abdominal. Given its rarity, diagnosis is often delayed until other pathology has been ruled out. We present the case of a 15-year-old boy with a one-year history of progressive fatigue, failure to thrive, and severe iron resistant, iron deficiency anemia. Extensive work-up revealed an intra-abdominal mass. At laparotomy, a discrete lymphoid-appearing mass was found at the base of the mesentery. Excision led to rapid and complete resolution of his symptoms, including resolution of anemia. Pathology demonstrated Castleman's disease of the hyaline vascular subtype. Increased awareness of this entity and its association with severe iron deficiency anemia though the overproduction of IL-6 may allow earlier detection and treatment. © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

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