Paediatrics Publications

Title

Canine pluripotent stem cells: Are they ready for clinical applications?

Document Type

Article

Publication Date

10-7-2015

Journal

Frontiers in Veterinary Science

Volume

2

Issue

OCT

URL with Digital Object Identifier

10.3389/fvets.2015.00041

Abstract

The derivation of canine embryonic stem cells and generation of canine-induced pluripotent stem cells are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms, and transplantation therapies in the dog. A progression from concept to cure in this clinically relevant companion animal will not only help our canine patients but also help advance human regenerative medicine. Nevertheless, many issues remain to be resolved before pluripotent cells can be used clinically in a safe and reproducible manner.

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