Paediatrics Publications
Title
CReSCENT: Cancer single cell expressioN toolkit
Document Type
Article
Publication Date
1-1-2021
Journal
Nucleic Acids Research
Volume
48
Issue
1
First Page
W372
Last Page
W379
URL with Digital Object Identifier
10.1093/NAR/GKAA437
Abstract
CReSCENT: CanceR Single Cell ExpressioN Toolkit (https://crescent.cloud), is an intuitive and scalable web portal incorporating a containerized pipeline execution engine for standardized analysis of singlecell RNA sequencing (scRNA-seq) data. While scRNA-seq data for tumour specimens are readily generated, subsequent analysis requires highperformance computing infrastructure and user expertise to build analysis pipelines and tailor interpretation for cancer biology. CReSCENT uses public data sets and preconfigured pipelines that are accessible to computational biology non-experts and are user-editable to allow optimization, comparison, and reanalysis for specific experiments. Users can also upload their own scRNA-seq data for analysis and results can be kept private or shared with other users.