Paediatrics Publications

Title

The challenges of assessing acute kidney injury in infants

Document Type

Article

Publication Date

9-2-2011

Journal

Kidney International

Volume

80

Issue

6

First Page

567

Last Page

568

URL with Digital Object Identifier

10.1038/ki.2011.172

Abstract

Definitions of pediatric acute kidney injury (AKI) use changes of serum creatinine. There is a paucity of well-designed studies in infants because of creatinine age-dependency. The emerging role of cystatin C as a superior marker of renal dysfunction led to a carefully conducted study on AKI in infants by Zappitelli et al. This Commentary calls for the development of age-independent serum creatinine and estimated glomerular filtration rate z scores. © 2011 International Society of Nephrology.

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