Title

Psychometric Properties of a Prostate Cancer Radiation Late Toxicity Questionnaire

Authors

George Rodrigues, University of Western OntarioFollow
Glenn Bauman, University of Western OntarioFollow
Michael Lock, University of Western OntarioFollow
David D'Souza, University of Western OntarioFollow
Jeff Mahon, University of Western OntarioFollow

Document Type

Article

Publication Date

5-31-2007

Journal

Health and Quality of Life Outcomes

Volume

5

Issue

29

Abstract

Background: To construct a short prostate cancer radiation late toxicity (PCRT) questionnaire with health-related quality-of-life (HRQoL) domains.

Methods: The PCRT was developed by item generation, questionnaire construction (n = 7 experts, n = 8 focus group patients), pilot testing (n = 37), item reduction (n = 100), reliability testing (n = 237), and validity testing (n = 274).

Results: Reliability of the three item-reduced subscales demonstrated intraclass correlation coefficients (CC) of 0.811 (GU), 0.842 (GI), and 0.740 (sexual). Discriminant validity demonstrated Pearson CC of 0.449 (GU-GI), 0.200 (sexual-GU), and 0.09 (sexual-GI). Content validity correlations between PCRT-PCQoL were 0.35-0.78, PCRT-FACT-G(c) were 0.19-0.39, and PCRT-SF-36(R) were 0.03-0.34.

Conclusion: We successfully generated a PCRT HRQoL questionnaire including subscales with very good psychometric properties.

Notes

Published in: Health and Quality of Life Outcomes, 2007, 5:29. doi: 10.1186/1477-7525-5-29