Microbiology & Immunology Publications
Use of adhesion counts to help predict symptomatic infection and the ability of fluoroquinolones to penetrate bacterial biofilms on the bladder cells of spinal cord injured patients
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Scanning and transmission electron microscopy of an antibiotic-treated infected urinary stone demonstrates a thick bacterial biofilm adhering to the surface of the stone. Cultures of the crushed calculi indicated the viability of the bacteria. Exopolysaccharide secreted by the bacteria develops a matrix or glycocalyx that appears to protect the biofilm forming sessile bacteria from antibiotics. © 1985.